The most common metastatic site of choriocarcinoma is lung, which can be clinically characterized by hemoptysis, chest pain, cough or dyspnea, and can be detected by chest X-ray or CT examination. Other metastatic route is vaginal metastasis, which can manifest as vaginal bleeding. The prognosis of metastasis to liver is poor, the fatality rate of metastasis to brain is high, and it can also metastasize to kidney, spleen, gastrointestinal tract, bones and other tissues. Choriocarcinoma can be triggered in ectopic pregnancy, miscarriage, preterm labor, full-term pregnancy, and gravida. Currently, it is mainly treated with chemotherapy and has a good prognosis. Detection of choriocarcinoma also includes laboratory tests, such as blood HCG, imaging tests, such as chest X-ray, and other detailed history and physical examination.