When an emphysema matures can be determined from the appearance and tactile sensation, etc. After maturation, an emphysema will show localized pus and white spots, and its texture will become soft and even fluctuating. The granuloma is an acute suppurative inflammation of the eyelid glands infected by bacteria such as Staphylococcus aureus. When the granuloma matures, an abscess is formed, and the inflammatory reaction such as redness, swelling, and pain will be more pronounced, and yellowish-white pus dots will appear, which are soft and even fluctuating to touch, and then may break out. Early immaturity is only manifested as a small localized swelling, there can be no obvious redness, swelling, pain and other inflammatory symptoms, this period of granuloma can be treated with hot compresses and local antibiotics, such as levofloxacin eye drops, etc., and do not have to wait until maturity will subside. The medication should be used according to the doctor’s instructions. Do not easily squeeze during the development of granuloma, local inflammation symptoms are serious, it is recommended to consult a doctor in a timely manner for appropriate treatment.