High urinary microglobulin generally indicates increased β2 microglobulin in urine, which generally suggests reabsorption dysfunction in the renal tubules. β2 microglobulin is a small molecular weight protein, molecular weight is 11800 Da, in the human body can freely pass through the glomerulus for filtration, after reaching the renal tubule, 99.9% will be reabsorbed by the renal tubule; and increased β2 microglobulin means that the renal tubular reabsorption dysfunction, which is likely to be related to the renal tubular damage induced by a variety of reasons. For example, hypertension can lead to hypertensive renal damage, acute interstitial nephritis and chronic interstitial nephritis, etc., all of which can induce increased β2 microglobulin. In addition, glomerular diseases combined with tubular lesions can also cause increased β2 globulin in the blood as well as increased β2 microglobulin in the urine. If you find that urinary β2-microglobulin is elevated, you should go to regular hospitals in time to receive relevant examinations, and under the guidance of physicians, actively treat the disease according to the cause.