There is no requirement that people with ankylosing spondylitis should not have sex, only that it is not recommended during an acute attack of ankylosing spondylitis. If the disease is under control and stable, you can have a normal sex life. Ankylosing spondylitis is a relatively common rheumatic disease, more common in men, the specific pathogenesis is not very clear, may be related to genetics, exercise, infection, physical and chemical factors, a part of the patient has a tendency to family aggregation, may be and HLA-B27 gene has a certain correlation. Ankylosing spondylitis clinically mainly manifested as low back pain, but also can appear peripheral joint pain, hip alternating pain and heel pain, at present, the most effective treatment of ankylosing spondylitis is biological agents, such as tumor necrosis factor antagonist.