The white granules on the nose are considered to be whitehead acne, and the methods of removal include general treatment, topical medication, oral medication, and medical aesthetic treatment. 1. General treatment:Generally for the case of whiteheads on the nose is relatively mild, has not yet formed acne, then you can remove the fat plugs or keratin through the cleaning and hygiene of the nose, it is recommended to use a mild cleanser, clean the nose, reduce the use of cosmetics. 2. Topical medication: If the whiteheads on the head of the nose are more obvious, you can use some adapalene gel, salicylic acid ointment, benzoyl peroxide, etc., anti-inflammatory, lipid treatment, to remove excessive whitehead particles. 3. Oral medication: If the whitehead particles are more serious and form acne, you can take oral antibiotic treatment, such as doxycycline, minocycline, etc.; you can also take isotretinoin orally to remove excessive oil particles and improve the symptoms, but isotretinoin has the side effect of teratogenicity, and is not suitable for men and women of childbearing age to take. 4. Aesthetic treatment: When the above methods are not effective, patients can also take fruit acid peeling, photorejuvenation and other aesthetic methods to improve the skin condition and remove white particles from the nose. It is recommended that patients according to their own situation, if necessary, to the regular hospital dermatology consultation, follow the doctor’s instructions reasonable use of medication, not blindly self-medication.