A feeling of pressure in the chest is mostly considered as lung disease, heart disease, neuropsychiatric disease, etc. Chest pressure can be clinically understood as chest tightness, shortness of breath, dyspnea, etc. It can be accompanied by other symptoms, such as panic, chest pain, coughing, coughing up phlegm and so on. 1. Lung diseases: such as lung inflammation, tuberculosis, emphysema, pneumothorax, etc., which lead to reduced function of lung suction and gas exchange, unable to provide enough oxygen, and the symptom of chest tightness will occur. 2. Heart disease: It is common in heart failure, most obvious in left heart failure. As the pumping function of the heart decreases, it leads to blood stagnation in the pulmonary circulation, which affects the function of the lung tissues in inhalation and gas exchange, resulting in hypoxic conditions. The symptoms are chest tightness and tightness in the chest. 3. Neuropsychiatric disorders: mainly due to high mental stress, hyperventilation, subjective chest tightness symptoms are more obvious, generally in the appeasement, rest can be relieved. There are other causes of chest tightness, so we suggest that patients seek timely medical attention to clarify the cause of the disease and actively treat it.