The causes of refractory hypertension include the following: 1, the most common cause is the measurement factor, the cuff is too loose or too tight, often resulting in elevated blood pressure; 2, genetic factors, such as parents with hypertension, the probability of children suffering from hypertension is higher; 3, lifestyle, such as young people smoking, drinking, staying up late, irregular life; 4, medication factors, clinically there are many patients, such as giving him prescription drugs, 1 day 2 The patient often reduces or stops the medication on his own, which makes it difficult to control blood pressure; 5, there are also secondary hypertension, such as the patient combined with renal artery stenosis, the blood vessels supplying the kidney have severe narrowing, the clinical blood pressure is very high, such as pheochromocytoma, the adrenal glands grow tumors, tumor secretion of substances to stimulate the body’s blood pressure suddenly increased, and blood pressure fluctuations.