Men who contract syphilis usually show symptoms in about 2 to 4 weeks. Syphilis is a chronic, systemic sexually transmitted disease caused by the syphilis spirochete, and the main modes of transmission are sexual, blood, and mother-to-child. The incubation period ranges from a few days to tens of days, with an average of 3 weeks. Syphilis can be categorized as Stage I, Stage II or Stage III depending on the course of the disease. Stage I symptoms are primarily a hard chancre, which can appear as painless nodules and occur primarily on the external genitalia. Stage II is characterized by a syphilis rash, which may appear as erythema and papules on the skin and may occur throughout the body. Stage III may include skin and mucous membrane damage, bone damage, eye damage, nerve damage, and cardiovascular damage. It is also possible for a male to contract syphilis with no obvious clinical symptoms. It is recommended that patients with high-risk behaviors who are worried about contracting syphilis should consult a doctor for a clear diagnosis in time to avoid delaying their condition.