Lipoprotein a 1300mg/L is significantly elevated and increases the risk of atherosclerosis and cardiovascular disease. The normal value of lipoprotein a is <300mg/L, which is a kind of apolipoprotein synthesized by the liver. Elevated levels of apolipoprotein will increase the risk of atherosclerosis, and long-term elevated levels will lead to significantly higher incidence of cardiovascular and cerebrovascular diseases, which is a risk factor for cardiovascular and cerebrovascular diseases, and the higher the levels are, the higher the risk of cardiovascular and cerebrovascular diseases. Patients with high ApoA should control their diets, avoid barbecue, animal offal and high-fat foods, eat more green and fresh vegetables, and reduce excessive fat intake through diet. Patients with significantly elevated ApoE can be treated with oral acyclovir, which can control ApoE levels and reduce the risk of cardiovascular disease. Acipimox belongs to the nicotinic acid class of lipid-lowering drugs, for triglycerides and cholesterol have a lowering effect, in particular, can control the level of lipoprotein A. Adverse effects of the drug include redness, itchy skin, abdominal pain, diarrhea, etc., for the drug ingredients allergy, severe liver function impairment, peptic ulcer, children, lactation and pregnancy is prohibited for women. Patients need to be treated under the guidance of a doctor, and should not use the drug without authorization.