The severity of multiple cerebral infarction is related to the location, size, number, comorbidity and age of the infarcts, which should be determined by combining clinical and examination. Some patients are prone to recurrence and sequelae. Multiple cerebral infarction is a special type of cerebral infarction. Compared with single cerebral infarction, the condition of multiple cerebral infarction is complicated and changeable, easy to progress, with poorer prognosis, high disability, death and recurrence rates, and it is the key and difficult point in the prevention and treatment of cerebrovascular disease in clinic. Generally speaking, the infarction site is located in the dominant hemisphere or brain function area such as medulla oblongata and cerebral bridge, etc. The larger the area, the more numerous, the older, the more combined diabetes, hypertension, obesity, heart disease and other diseases, the more serious its clinical manifestations, the worse the prognosis, easy to recur and leave sequelae. Multiple cerebral infarction is an acute and serious disease. Once patients are found to have symptoms such as dull expression, crooked mouth, blurred consciousness, slurred speech, and weakness of arms and legs, they should dial 120 and send them to the hospital for diagnosis and treatment as soon as possible so as to achieve early discovery, diagnosis, and treatment, and the better the prognosis will be.