12-year-old child dry cough without sputum can be seen in respiratory tract infections, cough variant asthma, upper respiratory tract cough syndrome, etc., what medication to take according to the etiology of the decision, such as upper respiratory tract infections, consider the bacterial infection caused by the use of cefixime, azithromycin and other anti-infective treatment. 1. Respiratory tract infections: such as acute bronchitis, children can be in the early stages of the disease or the course of the phenomenon of dry cough, may be accompanied by fever symptoms. If considering the possibility of mycoplasma infection or bacterial infection, antibacterial drugs such as cefixime or azithromycin can be used as appropriate for anti-infective treatment. 2. Cough variant asthma: it can be seen in this age group, and it can be characterized by dry cough, which is often recurrent, mostly at night, in the morning or after activities. Lung function can be improved to make a clear diagnosis. For these children, oral leukotriene receptor antagonists (such as montelukast sodium) can be used to reduce airway responsiveness, or nebulized inhalation of salbutamol, budesonide and other treatments. 3. Upper respiratory cough syndrome: this disease is often caused by rhinitis and sinusitis, due to the nasal secretions can not be timely drainage out, resulting in children with nasal secretions backflow, stimulation of the pharynx, resulting in coughing, can be under the guidance of the doctor to the negative pressure nasal suction, sputum, sea saline nasal spray strong and other operations. The above medications should be used under the guidance of a physician, do not use medications without authorization to avoid danger.