Knee swelling and pain does not exclude gout, but may also be caused by trauma or rheumatoid arthritis and other factors. 1. Gout: gout is a metabolic disease, the disease often involves the toes, ankles, knees and other joints of the lower limbs and lead to severe pain in the joints, fever and swelling of the joints and other symptoms, so patients with knee swelling and pain symptoms do not rule out gout. 2. Trauma: after the knee is injured by external force, due to local tissue and capillary damage, tissue fluid exudation, blood cell exudation and other factors will lead to the traumatized part of the swelling and pain symptoms. Therefore, knee swelling and pain may also be caused by trauma. 3. Rheumatoid arthritis: rheumatoid arthritis can involve the knee, ankle, wrist and other peripheral joints and lead to morning stiffness, joint swelling and joint pain and other symptoms, with the progress of the disease can also cause patients with joint deformity and activity restrictions. Therefore, patients with rheumatoid arthritis may have symptoms of knee swelling and pain. There may also be other causes of knee pain, gout patients are recommended to regular hospital orthopedics, rheumatology and immunology departments and other related departments for detailed consultation.