Generally, the main symptoms of gastrointestinal flu are nausea, vomiting, diarrhea, fever, headache, nasal congestion, runny nose, bloating and loss of appetite. Can choose celecoxib, ribavirin, montelukast and other drugs for treatment. In fact, in the clinical and gastrointestinal cold name, generally refers to the common cold caused by the gastrointestinal tract dysfunction, in addition to the common cold of the respiratory system and systemic symptoms such as headache, runny nose, nasal congestion, coughing, etc., the main manifestations of loss of appetite, nausea, vomiting, diarrhea, and other symptoms, with a self-limiting, self-cure. If the symptoms of vomiting and diarrhea are serious, there may be water electrolyte and acid-base balance disorders, and electrolytes and water can be supplemented; when watery diarrhea occurs, drugs such as montelukast can be applied for treatment; patients with immunodeficiencies can be treated with antiviral therapy using ribavirin and oseltamivir, etc.; anti-inflammatory, antipyretic and analgesic treatments can be used together with nimesulide and celecoxib. When symptoms of gastrointestinal flu occur, it is recommended to consult a doctor in time for targeted treatment under the guidance of a medical professional. In addition, the above drugs should be used under the guidance of a doctor, not unauthorized use of drugs.