Killing the nerve of the tooth generally has no effect on the heart, killing the nerve of the tooth with anesthesia may affect the heart, before killing the nerve of the tooth should be informed to the doctor’s physical condition. Killing dental nerve that root canal treatment, belongs to the stomatology more common treatment, the heart is one of the body’s internal organs, most of the oral treatment will not affect the heart, in general, kill the dental nerve for the heart has no effect. However, if anesthesia is used to kill the nerve of the tooth, patients with serious cardiovascular disease may experience accelerated heartbeat and induce heart failure, causing cardiac discomfort. Therefore, patients with serious cardiovascular disease should inform the doctor of their physical condition when they undergo dental nerve treatment, and the doctor will assess whether it is possible to kill the dental nerve.