The medical term for facial spasm is called facial muscle spasm, which refers to intermittent involuntary clonic twitching or painless tonicity of the facial muscles on one side of the face. The etiology of the disease is not yet fully understood, but reports have shown that most of the facial muscle spasms have a misrouted blood vessel pressing on the facial nerve root, which leads to abnormal excitation of the facial nerve, resulting in an abnormal discharge that causes the muscles to twitch. In addition, disorders such as vascular malformations, acoustic neuroma, brainstem infarction, and demyelination of the central nervous system can also lead to facial muscle spasms. The twitching increases during tension, exertion, and voluntary movement and stops after sleep. For treatment, local injection of botulinum toxin is preferred, and for medication, a variety of sedative and antiepileptic drugs can be chosen, which can reduce symptoms in some patients. Surgical treatment, if necessary, can be used for facial nerve microvascular decompression.