The normal reference range of platelets is (100-300)×10^9/L. Platelets high 380, which should mean 380×10^9/L, belongs to the platelets slightly high, such as other indicators are normal, and the patient does not have any uncomfortable symptoms, generally does not matter, usually does not affect the organism, pay attention to observation, regular review can be. If accompanied by other abnormalities, such as dizziness, weakness, blurred vision and other symptoms, should promptly go to the hospital to exclude other organic diseases: 1, physiological impact: in most cases, high platelets 380 × 10^9 / L is due to physiological factors, such as after exercise, after a full meal, after lunch, menstruation, can lead to high platelets, it is recommended to develop a good daily life, the diet, platelets can lead to high platelets. The platelets can be restored to the normal level; 2, pathological factors: high platelets may also be due to disease factors, such as chronic granulocytic leukemia, primary thrombocytosis, splenomegaly, acute infection, cancer, can lead to platelets appear 380 × 10^9/L, or even more than 400 × 10^9/L. The situation is more serious, should be clarified as soon as possible, the cause of the disease, using The cause should be identified and treated as soon as possible to avoid aggravation of the condition. In addition, if platelets are persistently high or severely high, it should be taken seriously and may lead to thrombotic diseases, such as cerebral infarction and myocardial infarction.