The main function of platelets is to clot and stop bleeding, so platelet count is an important indicator of blood health. If the value is high, first of all, we should regularly check whether the platelets are continuously increased, because the occasional increase of platelets may be physiological increase, if suspected of pathological increase should promptly go to the hospital to avoid delaying the disease. First, physiological increase: In the conditions of strenuous exercise, full meals, cold and other conditions in the body platelets will be released more, thus causing an increase in peripheral blood platelets, normal people will have certain fluctuations in the daily platelet count, generally lower in the morning and higher in the afternoon. In addition to this, the platelet count is also affected by the season of measurement, and is generally higher in winter compared to spring. All of the above are normal physiological phenomena, no special treatment; 2, pathological increase: 1, myeloproliferative diseases: such as chronic granulocytic leukemia, true erythrocytosis, primary thrombocytosis, etc., the above diseases are primary thrombocytosis, treatment is mainly to prevent thrombosis and bleeding, at this time should be under the guidance of the doctor with drugs or surgery; 2, infection: suffering from chronic inflammatory diseases The platelet reactivity is increased when the patient is recovering from acute infections, such as rheumatoid arthritis, acute rheumatic fever, periarteritis nodosa, Wegener’s granulomatosis, ulcerative colitis, tuberculosis, nodular disease, chronic lung abscess, osteomyelitis, etc., and in the recovery period of various acute infections, the cause of which needs to be identified at the hospital before treatment; 3, anemia: platelet increase due to acute and chronic blood loss is a protective reaction of the body, generally bleeding Platelets can return to normal after control. In patients with iron deficiency anemia, platelet count can be normalized after iron supplementation. Hemolytic anemia needs to be treated under the guidance of a doctor and can return to normal after the condition is controlled; 4. malignant tumors: platelets may be increased in patients with malignant tumors and it is recommended to actively treat the primary tumor, in addition, such patients should pay attention to the prevention of bleeding and thrombosis due to disorders of the coagulation system; 5. other: platelets may be increased after splenectomy. The spleen can engulf the aging cells in the blood, so the platelets increase within 1 week after splenectomy, and usually can return to normal within 2 months. Some drugs can also appear as mentioned above, such as epinephrine and interleukin-1β can increase platelet reactivity, which can gradually return to normal after stopping the drugs.