Common causes of acute poisoning include occupational poisoning and life poisoning. Occupational poisoning refers to exposure to toxic materials, intermediate products or finished products in the production process, which can occur if no attention is paid to protection; poisoning can also occur if the safety protection system is not observed in storage, use and transportation. Life poisoning is common in cases of accidental ingestion, accidental contact, overdose, suicide and murder. The patient should be taken out of the poisoned state immediately. If it is contact or inhalation poisoning, the patient should be made to leave the poisoned place, take off the contaminated clothes and wash the skin with warm boiled water. If there is trauma, the trauma should be cleaned and bandaged, and the unabsorbed poison in the body should be removed. The unabsorbed poison in the gastrointestinal tract can be removed in the following ways: 1. Emetic. The indications for emetic are patients who are clearly conscious and can cooperate. Contraindications are coma, convulsions, eating strong acidic objects, kerosene, gasoline, and should be used with caution in old and frail patients, pregnant with high blood pressure and heart disease; 2. Gastric lavage, indications are comatose and uncooperative patients, should be performed as early as possible, usually within 6 hours after taking the drug, contraindications are corrosive poisons, strong acids, strong bases are not suitable for use; 3. Induced diarrhea, indications in taking poisons more than 4 hours; 4. Enema. In addition to corrosive poisoning, it is applicable to those who have been poisoned orally for 6 hours, and those who have not been effective in inducing diarrhea, or even drugs that inhibit intestinal peristalsis, can use 1% soapy water in high level for several consecutive enemas; 5. Remove the poison from the skin, eyes and wounds, and if the poison is splashed into the eyes, it should be washed with water immediately. If you are bitten by a poisonous snake, you should quickly bandage the wound at the proximal end, clean it thoroughly, remove the surrounding tissues and any venom that may remain in the wound, and flush it repeatedly to promote the discharge of absorbed venom, which can be accelerated by drinking a lot of water and intravenous fluids to increase the amount of urine.