Hand, foot and mouth disease care should pay attention to the general care of ordinary cases, severe cases of close supervision, local medication to promote healing, as follows. 1. General care: ordinary cases pay attention to isolation, avoid cross-infection, appropriate rest, diet should be light. 2. Close monitoring: severe cases should be closely observed, closely monitored, and keep the airway open. 3. local medication: mainly for oral lesions, anti-inflammatory analgesic, promote healing. 0.1% ~ 0.2% chlorhexidine gargle, lidocaine local analgesia, it is recommended to use the medication under the guidance of a doctor, do not blindly self-medication. Pay attention to the observation of the patient’s state, if the patient has persistent fever, poor mental health, vomiting and other symptoms, go to the hospital in a timely manner, early formal treatment.