GERD can be completely cured using a combination of medicinal methods and surgery, but it is important to pay attention to lifestyle changes after the cure. 1. Drug therapy: to promote the emptying of esophagus and stomach, you can use to promote gastrointestinal peristalsis such as cisapride; to reduce gastric acid, you can use acid inhibitors such as omeprazole, H2 receptor antagonists such as Ranitidine, gastric mucosal protectants such as thioglycollate and so on, all of the above drugs need to be applied under the guidance of a physician, to avoid the use of medication privately. 2. Surgery:Through fundoplication surgery, the anterior wall of the fundus of the stomach is folded and wrapped around the lower esophagus and sutured, which allows the lower part of the esophagus to pass through the gastric muscle, strengthens the valve and prevents acid reflux. Post-operative life also requires small, frequent meals that are not too filling, and avoiding lying flat after meals, etc. Gastroesophageal reflux disease, it is recommended to regulate the treatment under the guidance of a doctor.