White spots on the tongue that can’t be scraped off may be leukoplakia, or it may be due to lichen planus or hyperkeratosis of the mucous membranes. 1. leukoplakia: the main manifestation of white patches or plaques at the blood penetration, occurs mostly due to. Physical and chemical long-term. Stimulation or the presence of genetic factors induced mucosal precancerous lesions, will be manifested as a white spot on the tongue can not be scraped off. 2. lichen planus: lichen planus belongs to mottled disease which will be presented as white stripes in the tongue, the reason for its occurrence is related to genetic mental systemic condition, and it belongs to pre-cancerous state, which may be manifested as white spots on the tongue that cannot be scraped off. 3. Excessive keratinization of mucous membrane: due to bad dietary habits or frequent chewing of betel nut, the mucous membrane may be stimulated to appear excessive keratinization, which is a benign lesion, and may be manifested as white spots on the tongue that cannot be scraped off. The appearance of white spots on the tongue can not be scraped off the phenomenon, it is recommended to consult a doctor in a timely manner, to clarify the causative factors, and follow the doctor’s instructions for symptomatic treatment.