Liver hypoechoic border with blood flow signal may be related to hepatic hemangioma, hepatic cyst and other diseases. 1. Hepatic hemangioma: it is the most common benign tumor of liver, which is caused by the abnormal proliferation of blood vessels in the liver. Most of the hepatic hemangiomas are asymptomatic, but a small number of patients will have symptoms such as upper abdominal pain, nausea, vomiting, abdominal distension, etc. The examination can find hepatic hypoechoicity, clear boundaries, and blood flow signals, etc. Most patients do not need treatment, and patients with obvious symptoms can be treated by surgical resection or interventional therapy. Most of the patients do not need treatment, and those with obvious symptoms can take surgical resection or interventional therapy. 2. Liver cysts: a common benign liver lesion, such as parasitic infection, inflammation, trauma and other causes of liver cysts, there will be postprandial fullness, right upper abdominal pain and other symptoms, examination of liver hypoechoic border is clear and there is a blood flow signal, the effect of drug therapy is not very effective, can be treated by surgical decapitation decompression of cysts or cystectomy. Patients with hepatic hypoechoic border clear with blood flow signal should go to the hospital as soon as possible, under the guidance of the doctor for standardized treatment.