In the myelosuppressive stage of sepsis, symptomatic treatment should be carried out on the basis of general treatment and early application of antibacterial drugs such as piperacillin, vancomycin combined with ceftazidime, according to the condition. 1. General treatment and symptomatic treatment: patients should be instructed to rest in bed, given high-calorie and easy-to-digest diet, and supplemented with vitamins in appropriate amount to maintain water, electrolyte and acid-base balance of the patient’s body, such as the patient’s present hyperthermia, and physical hypothermia is given priority to. Correct the patient’s hypoproteinemia, give fresh whole blood, plasma and albumin if necessary. 2. Antimicrobial drug treatment: when the pathogenic bacteria are uncertain, myelosuppressed patients with immunocompromise and leukopenia, mostly consider S. aureus and Pseudomonas aeruginosa, vancomycin combined with ceftazidime can be given under the guidance of the physician. After clarifying the pathogenic bacteria, medication adjustment can be given according to the pathogenic bacteria and drug sensitivity. Myelosuppressive sepsis is generally an acute systemic infection that occurs due to the invasion of pathogenic bacteria into the blood circulation during myelosuppressive period when the body’s immunity is low. If the condition permits, drugs should be applied to shorten the myelosuppressive period and improve immunity, such as granulocyte colony-stimulating factor and interleukin-11 to promote platelet recovery. The treatment of leukemia during bone marrow transplantation must be based on the specific conditions of the patient, and specific treatment plans should be taken under the guidance of the doctor, once the diagnosis is confirmed, please go to the hospital in time and standardize the treatment. Drugs should all be used in accordance with medical advice.