Drug treatment is preferred for kidney stones smaller than 0.6cm, and 3mm kidney stones can be treated with drugs such as sodium bicarbonate of citrate for lithotripsy. For kidney stones smaller than 0.6cm, smooth surface, no obstruction in the urinary tract below the stone preferred drug treatment, different types of stones need different drugs. Pure uric acid stones as well as cystine stones should first be alkalized by sodium hydrogen citrate, sodium bicarbonate urine, produce stone dissolving effect, at the same time can be oral allopurinol with dietary regulation, the effect is better. Cystine stone treatment requires alkalinization of urine, acetylcysteine has a litholytic effect. Infectious stones should first control the infection, such as cefixime, etc., at the same time for stone dissolution, you can take oral ammonium chloride to acidify the urine, urease inhibitors can inhibit the growth of stones. Drug treatment process should increase fluid intake, including drinking large amounts of water, increase urine output, pay attention to a balanced diet, renal colic is mainly based on antispasmodic and analgesic drugs, common non-steroidal analgesic and anti-inflammatory drugs such as diclofenac sodium. All of the above drugs should be used under medical supervision.