Eye swelling and pain may be caused by eye fatigue, glaucoma, refractive error, etc. Patients can heal through medication, surgery and daily maintenance. 1. Eye fatigue: Eye fatigue can be caused by excessive use of the eyes, resulting in eye swelling and pain. Patients can use anti-fatigue eye drops, such as nafamivir eye drops, under the guidance of the doctor, while patients should pay attention to eye rest and reduce the use of electronic products. 2. Glaucoma: due to long-term adverse mental stimulation, trauma, etc. can lead to glaucoma, the patient will appear in the phenomenon of eye swelling and pain. At the initial stage, patients can use pupil shrinking agents such as Hirschsprung’s Eye Drops or β-adrenergic receptor blockers such as Metoprolol under the guidance of doctors for treatment, and if the symptoms are more serious, filtration surgery can be used for treatment. 3. Refractive error: Refractive error can be caused by genetic factors and irrational eye use, and patients will experience eye swelling and pain. Patients need to improve the bad eye habits, can be equipped with appropriate glasses to correct vision, if necessary, the use of surgical treatment. If the symptoms of eye swelling and pain are not relieved after resting and accompanied by other discomforts, it is recommended to consult a doctor in time for diagnosis and treatment by a professional doctor.