Menopausal women need to take estradiol, dydrogesterone and other hormonal drugs to regulate menstruation according to their own actual situation. Menopausal women have irregular menstruation, mainly due to the decline in ovarian function, what drugs can be taken to regulate menstruation can not be generalized, need to be based on the actual cause of women’s irregular menstruation to determine. First of all, the decline in ovarian function will lead to a significant reduction in the level of estrogen in the body, which leads to the endometrium can not be normal proliferation, can not form the menstrual flow, at this time, women can follow the doctor’s instructions to take estradiol, estradiol valerate and other estrogen drugs to supplement the body estrogen, so as to achieve the purpose of regulating menstruation. Secondly, the decline of ovarian function will also lead to non-ovulation or low ovulation, at this time, the low level of progesterone in the female body will lead to hyperplasia of the uterine lining can not be shed smoothly, thus irregular menstruation occurs. Women with irregular menstruation due to low progesterone levels can take progesterone, progesterone and other progesterone drugs under the guidance of a doctor for treatment. To summarize, what medication can be taken to regulate menstruation during menopause needs to be judged according to the hormone levels in the woman’s body, and it is recommended that the woman first consult a doctor for a hormone test, to clarify the specific cause of the disease and then give medication under the guidance of the doctor.