A creatinine of 151 umol/L is relatively not serious if it is caused by acute factors. If it is caused by chronic factors, it is relatively serious. Creatinine is an indicator of renal function, and elevated creatinine indicates renal failure. However, renal failure is divided into acute and chronic, and the severity of these two diseases is not the same. Acute renal failure can be cured in most cases, so creatinine 151umol/L is not very serious. After symptomatic support and detoxification treatment, patients may recover completely. However, if it is chronic renal failure, there is no possibility of recovery. The creatinine will gradually increase and eventually enter the uremic stage. Therefore, when judging whether creatinine 151umol/L is serious or not, we must distinguish whether it is acute or chronic. Clinically, the size of both kidneys is usually used to make the judgment. If it is chronic, both kidneys will shrink, if it is acute, both kidneys will be within the normal range or increase in size, you can perform ultrasound examination of both kidneys.