Varicella-zoster virus infection can involve the nerves, so late in the disease there is mainly pain, but also itching in some patients. The problem of itching includes several aspects of treatment: 1, you can systematically carry out pharmacological antihistamine and anti-allergy treatment, anti-allergy drugs, common loratadine, kairetan, reserpine, etc.; 2, you can apply topical creams, hormonal creams have a certain anti-itch effect, such as glucocorticoids, tretinoin urea cream, doxepin cream and anesthetic topical drug lidocaine cream can stop pain and itching; 3, you can carry out the corresponding Physical therapy, such as ultraviolet radiation or Chinese medicine cupping and bloodletting, electroacupuncture, fire acupuncture, acupuncture can be; 4, itching is unbearable, you can also use gabapentin, pregabalin analgesics, painkillers, painkillers not only have a pain-relieving effect, but also to reduce the role of central sensitization, to slow down the itching; 5, especially serious pain patients, consider using botulinum toxin injection therapy, if the injection of botulinum toxin can stop the pain, it should also be useful for patients with itching. It should also have a certain effect on itchy patients. But the cost is more expensive, so not particularly serious patients, it is recommended that the front method is the main.