Kidney diseases mainly include glomerulonephritis, nephrotic syndrome, renal insufficiency and so on. For the treatment of kidney disease, the focus is on early detection, early diagnosis and early medication, such as glomerulonephritis in the early stage of the application of ACEI and ARB drugs, the current representative of the drug is mainly Irbesartan, valsartan, Benadryl and so on. For nephrotic syndrome, it is still mainly through the examination of renal puncture to clarify the specific type of pathology, so as to target the choice of hormone or combined immunosuppressant treatment. At present, the latest type of immunosuppressant mainly include tacrolimus, cyclosporine, in addition to these drugs there are also some biologics, which are drugs developed in recent years, and they are also effective in the treatment of kidney disease. The most commonly used one is rituximab, which is mainly used for the treatment of membranous nephropathy. Patients who have adverse reactions to hormones and immunosuppressants or cannot tolerate them can try to apply the treatment of this biological agent.