Male semen leukocyte peroxidase staining is a cytochemical stain used to aid in the diagnosis of male dyszoospermia. The normal value of male semen leukocyte peroxidase staining ranges from <1, the higher the value, the higher the number of malformed spermatozoa, the higher the chance of causing male infertility. There are many causes of malformed sperm, and common genitourinary infections, acute mumps complicating orchitis, epididymal tuberculosis, alcoholism, smoking and other high-risk factors are induced. If a man detects abnormal leukocyte peroxidase staining, it is recommended to follow the doctor’s instructions to improve the relevant examinations to clarify the cause of the disease and take appropriate treatment to avoid serious consequences.