Pediatric enemas are a form of fever reduction in which medications with antipyretic effects are given into the body through the anus to reduce fever. Some drugs with antipyretic effect will be absorbed into the bloodstream in the rectum after entering the body through rectal administration, because they are not metabolized by the liver, so they are absorbed more directly, the fever is reduced more quickly, and the drugs take effect more quickly. However, due to the higher efficacy of the drug, the child may sweat more when the fever is reduced, which may easily lead to dehydration. Parents should pay attention to replenish the water for the children to avoid dehydration after the enema to reduce fever. In addition, in the process of rectal administration, it is easy to cause damage to the mucous membrane of the rectum of the child, parents should not self-enema for children. Children with fever need to go to a professional hospital for examination, to clarify the cause of fever, and then targeted treatment and treatment.