Symptoms of syphilis in men are manifested as a hard chancre in stage I, a generalized rash may appear in stage II, and stage III syphilis may invade the nervous, skeletal, cardiac, and other systems. The clinical symptom for men with stage I syphilis is a hard chancre, with the favored sites being the penis, glans, coronal sulcus, prepuce, and urethral opening. Stage II syphilis is characterized by a syphilitic rash with systemic symptoms, which usually reoccurs after the hard chancre has subsided, separated by an asymptomatic period. Flat warts may also be present, appearing as oval and irregularly shaped smooth-surfaced stromal-like papules. The third stage of syphilis is known as neurosyphilis, which affects the central nervous system, osteosyphilis, and cardiovascular syphilis, which affects the heart. Syphilis is a contagious disease, and the pattern of the rash is related to the type of sexual behavior at the time of infection and the duration of the disease, but not to gender. Syphilis symptoms are many, if the above similar symptoms, it is recommended to go to a specialized hospital for examination, so as to avoid delaying the condition.