If severe onychomycosis pierces the foot, then the patient needs to go to the hospital for professional medication, surgery and physical therapy. 1. Drug treatment: if the lesion has inflammatory reaction, but no abscess, then you can choose chlorhexidine solution for rinsing, you can also choose anti-inflammatory and antibacterial drugs such as Jinhuangxuan and ichthyolite ointment for external application; if the lesion is infected by bacteria, you can also choose antibiotics for treatment, such as cefixime and so on. If the lesion is infected by bacteria, antibiotics such as cefixime can also be chosen. 2. Surgery: If the situation is more serious, surgical treatment can be chosen, such as incision and drainage of abscess or nail extraction. 3. Physical therapy: patients can also choose infrared therapy and ultra-short wave physical therapy. In the case of severe onychomycosis, patients need to go to the hospital for professional treatment.