The instructions for Gui Fu Di Huang Wan are not yet clear about its adverse reactions (harmful effects), but the drug should be used in accordance with medical advice. Gui Fu Di Huang Wan is a tonic Chinese patent medicine with the effect of warming and tonifying kidney yang (warming and replenishing the yang energy of the kidneys). It has the effect of warming and replenishing kidney yang and is used in treating kidney yang deficiency (lack of yang qi in the kidneys), soreness and coldness of the waist and knees, swelling of the limbs, incontinence of urine (unsmooth urination) or reboundness, phlegm and drink (pathological products formed as a result of impaired metabolism of water and fluid), wheezing and coughing and thirst-quenching. Its contraindications are prohibited for those who are allergic to cinnamon, Radix et Rhizoma Polygoni Multiflori, Radix Rehmanniae Praeparata and other ingredients contained in Dihuang Pill with Gui Fu, and it is not suitable for those with Yin deficiency and internal heat. This product contains pungent, warm and hot products, such as pregnant women should be used with caution. This product contains epiphyllum, and should not be used with Semen xia, Psidium guajava, smallpox pollen, Chuanbei, Acanthopanax, Ampelopsis, and Baihe. It should not be used with cinnamon. During the period of taking the medicine, it is advisable to abstain from sexual intercourse; avoid eating cold and greasy food, in order to prevent cold from injuring the yin. Cinnamon and other warming medicines in this product should not be taken for a long time. Its adverse reactions are not clear, such as the need for medication needs to be in the traditional Chinese medicine diagnosis, rational use, do not take on their own, so as not to delay the condition.