Penicillin shots are gender-neutral and can be given intramuscularly or intravenously. Penicillin belongs to a class of antimicrobials, which includes benzylpenicillin, penicillin G, procaine penicillin, benzathine, cloxacillin and so on. General injection of penicillin can be injected through intramuscular injection, often in the lateral gluteus maximus muscle, but need to avoid long-term injection in the same area, so as to avoid the emergence of localized mass of the situation. Because penicillin is prone to anaphylaxis, patients need to conduct skin tests before using penicillin, and if there is no positive reaction to penicillin, then it can be used. Penicillin should be contraindicated in patients with a history of allergy to penicillins, or in patients with a positive penicillin skin test. Some patients may experience allergic reactions such as rashes, papules, and itching during penicillin use. If patients during the use of penicillin, need to combine their own situation, under the guidance of the doctor, do not unauthorized use of drugs, if there are symptoms of physical discomfort, need to report to the doctor in a timely manner, so as not to damage the health. During the treatment period, it is necessary to ensure sufficient rest time, do not overwork.