Adrenal nodules causing hypertension can take captopril. Adrenal gland is an important endocrine organ in human body, which can secrete saline corticosteroid, glucocorticoid, epinephrine, etc.; adrenal nodules can lead to high blood pressure by secreting hormones, which can cause secondary hypertension, while captopril is a kind of angiotensin-converting enzyme inhibitor, which can be used to treat high blood pressure caused by adrenal nodules on the body. Captopril inhibits the angiotensin-converting enzyme of the renin-angiotensin-aldosterone system (RAAS system), thus preventing the production of angiotensin, and inhibits the secretion of aldosterone and reduces sodium retention, thus lowering the blood pressure. The drug is suitable for the treatment of all kinds of hypertension, and is more effective in those with high plasma renin activity. Its adverse reactions mainly include headache, dizziness, nausea, vomiting, angioneurotic edema and so on. Contraindications are: renal insufficiency, severe autoimmune diseases; pregnant and lactating women, allergy; neutropenia, granulocyte deficiency patients. Specific treatment of hypertension drugs to consult a professional physician, under the guidance of the physician standardized treatment, do not take medication without authorization, in order to avoid adverse consequences.