Black spots on the skin may be caused by nevus cell nevus, perikeratosis or blackhead acne. It is recommended that patients be treated with oral medication, topical medication, phototherapy and surgery after the specific cause is clarified under the guidance of a doctor. There is no such thing as the most effective way to treat nevus due to the different degree of individual physique and severity of the disease. 1. Nevus cell nevus: Nevus cell nevus is a benign tumor formed by the proliferation of melanocytes. It can be treated with laser and other photoelectric therapies, or it can be surgically removed. 2. Keratosis Pilaris: Keratosis Pilaris is a hereditary skin disease. It can be treated with topical retinoic acid cream or salicylic acid cream. In serious cases, you can take oral vitamin A and other drugs. 3. Blackheads and pimples: Blackheads and pimples are caused by excessive oil secretion that clogs the pores of the hair follicles and oxidization that occurs at the same time. In the treatment, you can use topical adapalene gel, benzoyl peroxide and so on to improve. Or chemical peel treatment with fruit acid peels can also be useful. For patients with black spots on the skin, it is recommended to go to the regular hospital in time for examination, clear diagnosis, symptomatic treatment, and drugs need to be used as prescribed by the doctor.