Rebound pain in the lower abdomen is a sign of inflammatory involvement of the peritoneal wall and is most often seen in cases of intra-abdominal organ lesions involving the adjacent peritoneum and primary peritonitis. Gently pressing on the painful area, then quickly lifting the hand, and having a distinct pain at the moment of lifting the hand is called rebound pain, which often represents inflammation of the peritoneum where the pressure is applied. So, what are the causes of lower abdominal rebound pain? The following is a brief introduction: abdominal rebound pain is most often seen when intra-abdominal organ lesions involve the adjacent peritoneum, and also in primary peritonitis. Appendicitis is an inflammatory change of the appendix due to a variety of factors. It is a common disease and its prognosis depends on timely diagnosis and treatment. With early diagnosis and treatment, patients can mostly recover in a short period of time with a very low mortality rate (o.1% a 0.2%); if the diagnosis and treatment are delayed it can cause serious complications and even death. Post-abortion gynecological disease, abdominal aortic aneurysm, acute appendicitis in AIDS patients, colonic torsion, and acute peritonitis can all cause lower abdominal rebound pain.