Children have more opportunities to apply cephalosporins, which have good killing effect on bacterial infections, and cephalosporins have better safety and better efficacy. Cephalosporins are mainly divided into the following categories: First, the first generation cephalosporins. The first generation cephalosporins can treat Gram-positive cocci, such as applying cefadroxil or cefradine to children. Second, the application of the second generation of cephalosporins. Second-generation cephalosporins have a certain effect on killing Gram-positive cocci and Gram-negative bacilli, and have a wide antibacterial spectrum, such as cefaclor for children. Finally, the application of third-generation cephalosporins. The third-generation cephalosporins mainly focus on Gram-negative bacilli, such as the application of cefixime to children.