Swollen earlobes that turn red are mostly caused by secondary infection of sebaceous cysts in the earlobe, local inflammatory infections, allergies, etc. They can be treated by incision and drainage, antibacterial drugs, anti-allergy drugs, etc. 1. Earlobe sebaceous cyst secondary infection: mostly due to sebaceous gland opening blockage, sebum retention can not be discharged resulting in sebaceous cysts, secondary infection of the earlobe swelling redness and enlargement. Penicillin, cephalosporin antibiotics, such as amoxicillin, cefuroxime anti-infection treatment can be applied, and surgical incision and drainage can be used for treatment if necessary. 2. Local inflammation and infection: local infection after ear piercing can cause redness and swelling of the earlobe, you can apply local iodophor disinfectant, erythromycin ointment, mupirocin cream and other anti-infection treatment. 3. Allergy: you can locally apply weak glucocorticoid drug anti-allergy treatment, such as hydrocortisone butyrate cream, budesonide cream and so on. The symptoms of swollen earlobes become red and big, it is recommended to consult the hospital, diagnosed clearly and follow the doctor’s instructions for medication and treatment.