Metformin Hydrochloride Extended-Release Tablets can play a role in lowering blood sugar, which can easily cause gastrointestinal reactions, hypoglycemia and other side effects. Metformin extended-release tablets are mainly used for adults with type 2 diabetes mellitus who are ineffective in controlling blood glucose by simple dietary control and physical exercise. The drug can inhibit the output of hepatic glycogen, strengthen the sensitivity of muscle tissue to insulin, and help lower blood sugar. This improves the symptoms of hyperglycemia. For overweight diabetic patients, it can reduce the risk of cardiovascular disease caused by obesity. Metformin extended-release tablets have certain side effects, such as easy to lead to nausea, vomiting, diarrhea, dyspepsia, stomach bloating and weakness and other abdominal discomfort symptoms. Hypoglycemia may also occur when taken with other hypoglycemic medications or when used in combination with insulin. It is also likely to cause side effects such as weakness, or tiredness and weight loss. Metformin extended-release tablets are contraindicated in severe renal failure, acute metabolic acidosis, hepatic or renal insufficiency, and acute alcoholism. The dosage of Metformin Extended-Release Tablets should be adjusted according to the blood glucose level and avoid increasing or decreasing the dosage on your own.