Urticaria itchy at night, considering the night vagus nerve excitation caused by the treatment can be oral loratadine capsule, 1 capsule every night, combined with compound glycyrrhizin capsule, 3 times a day, 2 capsules for treatment. If the effect is not satisfactory, you can also inject chlorpheniramine maleate injection, once a day, once 1, combined with cyproheptadine hydrochloride tablets to achieve the effect of calming and itching, but also can be used externally with glycerite lotion with the treatment. For patients with excessive itching urticaria, you can also wet compress fresh amaranth, honeysuckle, cypress, forsythia decoction 200ml, twice a day, can achieve the effect of clearing heat and detoxification, cooling blood and calming. During the treatment period, you need to avoid spicy and irritating diet, including raw onion, raw garlic, chili peppers and so on.