When the platelet ratio is elevated, the first consideration is whether there is a problem with thrombocytosis or a cause such as decreased blood volume. It is important to assess the patient’s condition before deciding on a treatment plan. The platelet specific volume value is the percentage of the volume of platelets in the peripheral blood to the volume of whole blood. The platelet specific volume is related to the number of platelets, when the number of platelets increases while the blood volume remains the same, it will lead to an increase in the platelet specific volume, which is most commonly seen in thrombocythemia. Primary thrombocythemia, patients younger than 60 years of age, no cardiovascular and cerebrovascular disease is found, pay attention to follow-up observation. Patients older than 60 years of age, the presence of cardiovascular and cerebrovascular disease risk factors, need to be under the guidance of the doctor oral aspirin to inhibit platelet aggregation. When the blood volume decreases, such as when the patient has diarrhea or vomiting, it can also lead to an increase in the platelet count, which will return to normal after correcting the diarrhea or vomiting. For an increase or decrease in the platelet count, it is recommended to consult the hematology department of a regular hospital for analysis.