Swelling and pain in the forefoot may be caused by trauma, metatarsalgia, gouty arthritis and other diseases. 1. Trauma: Trauma to the forefoot area may cause damage to the local soft tissues or even fracture, resulting in swelling and pain in the forefoot. 2. Metatarsalgia: also known as metatarsalgia, mostly due to trauma, inflammation, foot deformity and other factors, after the onset of the patient’s forefoot bottom will be swollen and painful. 3. Gouty arthritis: It is an inflammatory disease of the joints caused by the deposition of urate microcrystals in the joints. The first onset of the disease is located in the first metatarsophalangeal joints, followed by ankles, dorsum of the foot and other parts of the foot, resulting in redness, swelling and pain in the forefoot and limitation of activities. In addition, there are many other causes of forefoot swelling and pain, it is recommended to go to the hospital in time to rule out physiological factors, and then early treatment.