1, Eugenol should be taken every day. 2, missed dose: If you miss a dose, you can take twice the dose on the next day. If you miss more than one day, you should insist on taking twice the dose for multiple days until you make up for the missed dose. 3, time: take 1 hour before breakfast, 3 hours after dinner (before bedtime), half an hour before breakfast, three kinds of taking time absorption efficiency in order to reduce, half an hour before breakfast is the bottom line to adhere to. 4.Blood draw: ask for blood check on an empty stomach and take the medicine after the check. 5, review cycle: after surgery oral eugenol patients need to review the nail function in the 6th week, thereafter, within 1 year after surgery, generally 3-6 months to review once, 1 year after surgery, can be 6 months to review once. It is important to note that whenever there is a change in the dose of medication, etc., it is necessary to wait 6 weeks for a review, at least 4 weeks. The reason is that the half-life of Eugenol is 7 days. 6. Affects absorption: Take with water only. Some special drugs or foods should be taken after sufficient time interval: 1 hour interval with vitamins, hypertension drugs, tonic; 2 hours interval with iron and calcium containing foods or drugs; 4 hours interval with milk and legumes; 12 hours interval with anti-cholestatic amines or lipid-lowering resins. Note: Eugenol is absorbed in the small intestine; the acidic pH of the stomach in the fasting state is more important for the absorption of the tablets in the small intestine, so it is important to assess the function of the gastrointestinal tract, such as HP-related gastritis, atrophic gastritis, and fat drainage, by taking more than the expected dose. After the disease is cured, thyroid function and levothyroxine dose need to be re-evaluated; the best absorption of the drug is 70-80%; eating affects absorption; fiber and grape juice are not found to affect absorption at present; soy products affect absorption; coffee affects absorption. 7, eugenol dose is enough or not, should be based on the final blood check. 8, eugenol and human secretion of thyroxine molecular formula is the same, the vast majority of patients can tolerate. Very few patients have symptoms such as “headache, palpitations, anxiety”, but the patient’s thyroid function may be normal, please consult your doctor, there are ways to relieve or even eliminate the symptoms. 9. Side effects of overdose – atrial fibrillation, osteoporosis; insufficient dose affects lipid metabolism and cardiovascular disease progression. Please consult your physician, the dosage should be individualized. 10. Change to other products, such as Retis, also levothyroxine sodium tablets, TSH levels need to be re-evaluated. 11. The dose of medication before and during pregnancy needs to be adjusted according to the TSH level in a timely manner, please consult your physician. 12. If the thyroid gland has been completely excised and radioactive iodine treatment is required after surgery, you cannot take or need to stop taking Eugenol before, for two reasons: TSH is suppressed after taking the medication, which affects the absorption of iodine; thyroxine tablets themselves are iodine-containing drugs.