Oral sulfonamides such as sulfamethoxazole or quinolones such as levofloxacin can be used for chronic UTI in women. Women’s chronic urethritis is mostly re-infection or recurrence, the causes include urethra has stones, obstruction or anatomical structure of the abnormal, treatment should be the first to remove these triggering factors, urine bacterial culture and drug sensitivity test, according to the results of the drug sensitivity test, reasonable choice of antibiotics, the course of treatment for at least 6 weeks, such as still recurring episodes, can be given to the long course of low-dose bacteriostatic therapy. Specific methods: half of the regular dose after urination before bedtime, can choose sulfamethoxazole or levofloxacin, etc., every 7-10 days to change the drug, continuous use for six months.