Dermaplanin is not usually used by women during pregnancy, and the drug instructions for Dermaplanin clearly state that it should be used with caution by women during pregnancy and lactation. Dexamethasone is a glucocorticoid and contains many phenolic substances that are highly permeable and can be easily absorbed into the skin, which is detrimental to the health of the fetus and can even cause fetal malformations. The actual fact is that, in some special cases, pregnant women can occasionally use dermaplanin in a small area under the guidance of a doctor without affecting themselves and the fetus, but if used in a large area for a long time, it is more harmful. When skin inflammation occurs during pregnancy, the main topical medications that can be used include glyburide lotion and some milder glucocorticoid medications such as dinaide cream and hydrocortisone butyrate cream, and also vitamin E cream can be used topically for temporary relief. When some topical medications are not effective, pregnant women can follow medical advice to add oral medications to control the patient’s condition, such as oral vitamin C and calcium gluconate. Also, the use of flower lotions and cosmetics should be avoided during pregnancy to prevent adverse effects on the fetus.