High total bile acids may be related to hepatitis, biliary obstruction, cirrhosis and other diseases, and patients may have diarrhea and other symptoms. 1. Hepatitis causes high total bile acid leading to diarrhea: Hepatitis is an inflammatory disease of the liver caused by microbial infection, immune response, drug action and other factors, and the patient mainly manifests nausea, vomiting, anorexia, scleroscleral yellowing of the skin, diarrhea, abdominal pain and other symptoms. 2. Biliary obstruction causing high total bile acid leading to diarrhea: biliary obstruction refers to the mechanical obstruction of bile ducts caused by a variety of factors such as bile duct stones, bile duct inflammatory stenosis, bile duct tumors and other factors that cause bile excretion is not smooth or completely blocked, the early patients may have symptoms such as yellowing of the skin, yellowing of the sclera and so on, and as the disease develops, the patients may have diarrhea, fever and other conditions. 3. Cirrhosis caused by high total bile acids leading to diarrhea: cirrhosis is a chronic progressive liver disease, in the compensatory phase, most patients are asymptomatic or less symptomatic, in the compensatory phase, patients may experience lethargy, fatigue, nausea, abdominal distension, and easy to eat meat diarrhea and other conditions. It is recommended that patients seek medical examination in time to clarify the cause of the disease and then carry out targeted treatment, pay attention to rest in life, avoid strenuous exercise, and also do a good job of monitoring the condition, once the condition worsens, it should be timely to seek medical treatment.