For medial collateral ligament injury of knee joint, the treatment is mainly to reduce swelling and pain in the acute stage, and the corresponding treatment is chosen according to the severity in the recovery stage, which can be general treatment, drug treatment and so on. For other severe injuries, surgery can be chosen. 1. Acute stage (1) Braking and resting: when the knee joint medial collateral ligament is injured, we should stop the exercise immediately, brake and rest to protect the affected area and prevent aggravation of the injury. (2) Ice: Ice should be applied immediately, which is very crucial in the early stage of sports injury. (3) Apply pressure bandage: After applying ice, apply pressure bandage to the affected area in time, and brake the injured area to reduce bleeding and oozing. (4) Elevate the affected area: Elevate the affected area as much as possible and higher than the position of the heart, which is conducive to reduce swelling and pain, and reduce bleeding and exudation. 2. Recovery period (1) General treatment: If the injury is mild, rest, ice and compression bandage are the only treatments needed, and the patient can usually return to normal function and activity within a few days. If the injury is moderate, it is necessary to limit the angle of joint activities under the protection of the brace for 4~6 weeks to avoid aggravating the ligament injury. (2) Medication: If the pain symptoms are severe, oral non-steroidal anti-inflammatory drugs, such as ibuprofen, diclofenac sodium, acetaminophen, etc., are helpful to reduce the pain symptoms. (3) Surgical treatment: If the patient has obvious instability of the knee joint and lateral collateral ligament injury accompanied by cruciate ligament injury, surgical treatment is usually chosen. All of the above medications should be used under the guidance of a doctor, avoid self-medication.