Increased non-squamous epithelial cells in urine may be caused by chronic pyelonephritis or chronic inflammation of the bladder mucosa, which requires further examination, including urine culture, cystoscopy, and CT examination of the urinary system to clarify the diagnosis. If it is chronic pyelonephritis, you can choose sensitive antibiotics, such as furantoin tablets and sulfadiazine tablets for 2-4 weeks of continuous oral treatment. After the chronic pyelonephritis is controlled, the non-squamous epithelial cells in the urine will slowly decrease. If chronic bladder mucosal inflammation is clearly identified through examination, the non-squamous epithelial cells in the urine will also be slowly reduced after the diseased mucosa is removed through transurethral resection of the bladder mucosa. During the treatment period, you can also take some oral Chinese medicine to clear heat and dampness, such as Sanjin tablets, Hot Lin Qing capsule, and Bazheng capsule also have very good effect.